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Tzung-Yan Lee

Tzung-Yan Lee

Associate Professor
Chang Gung University


Tzung-Yan Lee has completed his PhD degree from National Yang-Ming University and Postdoctoral studies from Institute of Biological Chemistry, Academia Sinica. He has published more than 50 papers in reputed journals and has been serving as an Editorial Board Member of repute.

Research Interest

My Research Focus on Hypoxia signaling in hepatic fibrosis and constructive creates new herbal remedy for liver diseases. Through current assay platform, we found that hypoxia signal triggers an ECM formation cascade leading to the mitochondria dysfunction and selective pathways of lipid and carbohydrate metabolism abnormity that is the main key of hypoxic response in liver diseases. Based on these findings, our lab is currently conducting experiments to elucidate the molecular mechanism of fatty liver in obesity. We are also investigating the roles of microbiota in regulating bile flow during hypoxia signaling in obese studies.