Noorul Hasan
Faculty of pharmacy, Integral University, Lucknow-226026, India
Title: Advancement of Herbal Drug Therapy for Cognitive Impairment in Animal Model
Biography
Biography: Noorul Hasan
Abstract
Nootropics drugs are also called as smart drugs. They are reported to improve mental function such as cognition, memory, intelligence, motivation, attention, and concentration. They are considered to be work by altering the availibility of neurochemicals, by improving the brains oxygen supply or by stimulating nerve growth. Some neurodegenerative disorder affects older individuals. Evidence supports the use of Ginkgo biloba, Huperzine A, Galantamine, Melissa officinalis and Salvia officinalis for Alzheimer’s disease. Plantago ovate, Azadirachta indica, Bacopa monniera for Parkinsonism disease. St. John’s wort, Lavender, Bryophyllum Pinnatum, Clitoria ternatea and Saffron for depression; Passionflower, and Kava, for anxiety disorders; Valerian, and English Lavender for sleep disorders; Butterbur root for a migraine; Withania somnifera possess both antistress as well as nootropic activity. The ethanolic extract of Nelumbo nucifera Gaertner seeds shows nootropic activity on Conditional avoidance response, Morris water maze for spatial learning, but it weakly acts on acetylcholinesterase enzyme inhibitory activity. In Invivo methods of the inhibitory passive avoidance, the test was carried on animals to test the learning and memory capacity of the animal by suppressing a particular behavior.